Key result
Over ~50% of first-degree relatives of premature CAD patients exhibit multiple atherosclerosis risk factors.
Why the study?
The prevalence of coronary risk factors among first-degree relatives of patients with premature coronary artery disease and their comparison with the general population was not well characterized.
What is the prevalence of coronary risk factors among first-degree relatives of patients with premature coronary artery disease compared to the general population?
Cross-Sectional (n=144)
What is the prevalence of coronary risk factors among first-degree relatives of patients with premature coronary artery disease compared to the general population?
First-degree relatives of patients with premature CAD have a high prevalence of coronary risk factors, highlighting the need for targeted screening and modification in this population.
Supports targeted screening of first-degree relatives; leaves open whether interventions improve outcomes.
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Saghafi et al. (2006) conducted a cross-sectional in First-degree relatives of patients with premature coronary artery disease (n=144). Family history of premature coronary artery disease vs. General population (Tehran University Population Laboratory Study) was evaluated on Prevalence of coronary risk factors. First-degree relatives of patients with premature coronary artery disease had a high prevalence of coronary risk factors, with ≥2 atherosclerosis risk factors found in 76% of men and 50.3% of women.
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