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March 19, 2012Therapeutic Apheresis and Dialysis

Morning Hypertension Determined by Self‐Measurement at Home Predicts Left Ventricular Hypertrophy in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis

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Key result

Morning systolic BP ≥135 mm Hg linked to ~16-fold higher LVH odds in CAPD patients.

  • OR 15.9
  • 95% CI 1.3 to 198.5
  • n=33

Why the study?

The relationship between self-measured morning blood pressure and left ventricular hypertrophy in patients undergoing continuous ambulatory peritoneal dialysis was unclear.

Does self-measured morning hypertension predict left ventricular hypertrophy better than hospital blood pressure in patients undergoing continuous ambulatory peritoneal dialysis?

Population

33 patients undergoing continuous ambulatory peritoneal dialysis, mean age 64.0 years

Comparison

Self-measured morning blood pressure at home vs hospital blood pressure measurements

Design

Cross-sectional study

Authors

HTHiroyuki TerawakiTSToru ShodaMOMakoto Ogura

Discussion

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Member takes

Overview

Morning hypertension may flag LVH risk in CAPD; hypothesis-generating and requires prospective validation versus office BP.

Study Design

Type

Cross-Sectional (n=33)

Structured PICO

Does self-measured morning hypertension predict left ventricular hypertrophy better than hospital blood pressure in patients undergoing continuous ambulatory peritoneal dialysis?

P
Population
33 patients (mean age 64.0 years) undergoing continuous ambulatory peritoneal dialysis.
E
Exposure
Self-measured morning blood pressure monitoring at home
C
Comparator
Blood pressure measured at hospital check-ups (hospital BPs)
O
Outcome
Left ventricular hypertrophy (LVH) determined by left ventricular mass (LVM) derived from echocardiographic examinationssurrogate

Main Result

Odds Ratio: 15.9 (95% CI 1.3–198.5)

Self-measured morning systolic blood pressure is a stronger predictor of left ventricular hypertrophy than hospital-measured blood pressure in patients undergoing continuous ambulatory peritoneal dialysis.

Cite This Study

Terawaki et al. (2012) conducted a cross-sectional in continuous ambulatory peritoneal dialysis (CAPD) (n=33). Morning systolic blood pressure ≥ 135 mm Hg vs. Morning systolic blood pressure < 135 mm Hg was evaluated on Left ventricular hypertrophy (LVH) (OR 15.9, 95% CI 1.3 to 198.5). Morning systolic blood pressure ≥ 135 mm Hg was significantly associated with left ventricular hypertrophy in patients undergoing continuous ambulatory peritoneal dialysis (OR 15.9; 95% CI 1.3-198.5).

synapsesocial.com/papers/6ab0cd22a36f39afe37fe9fbhttps://doi.org/10.1111/j.1744-9987.2012.01059.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Blood Pressure and Left Ventricular Hypertrophy in Patients on Different Peritoneal Dialysis Regimens2001 · 51 citations
  2. 2Out-of-Hemodialysis-Unit Blood Pressure Is a Superior Determinant of Left Ventricular Hypertrophy2005 · 182 citations
  3. 3Cardiovascular Prognosis of "Masked Hypertension" Detected by Blood Pressure Self-measurement in Elderly Treated Hypertensive Patients2004 · 850 citations
  4. 4Masked Hypertension Determined by Self-Measured Blood Pressure at Home and Chronic Kidney Disease in the Japanese General Population: The Ohasama Study2008 · 41 citations
  5. 5Prognosis of “Masked” Hypertension and “White-Coat” Hypertension Detected by 24-h Ambulatory Blood Pressure Monitoring2005 · 576 citations