Key result
Acute repetition exercise yields ~60% less improvement in vascular endothelial function vs interval exercise.
Why the study?
Few studies have investigated the effects of repetition exercise on vascular endothelial function compared to continuous and interval aerobic exercise.
Does repetition exercise improve vascular endothelial function compared to continuous or interval exercise in healthy males?
RCT (n=10)
Open-label
Randomized crossover
No
Does repetition exercise improve vascular endothelial function compared to continuous or interval exercise in healthy males?
Absolute Event Rate: 1.2% vs 3%
p-value: p=<0.05
Repetition exercise leads to less improvement in vascular endothelial function compared to high-intensity interval exercise in healthy males.
Repetition exercise may confer less acute endothelial benefit than interval exercise; extends modality comparisons in vascular responses.
High-intensity interval exercise (IE) leads to greater improvements in the arterial function than continuous exercise at moderate intensity (CE). However, few studies have been performed on the effects of the repetition exercise (RE) on the vascular endothelial function. The purpose of this study was to compare the effects of CE vs. IE vs. RE during aerobic exercise on the vascular endothelial function determined by flow-mediated vasodilation (FMD). Ten healthy male subjects randomly performed 3 trials as follows: CE (20-min cycling at 50%Wmax), IE (10 × 1-min intervals cycling at 75%Wmax interspersed with 1-min intervals cycling at 25%Wmax), and RE (30 × 20-sec intervals cycling at 100%Wmax interspersed with 20-sec intervals at rest). FMD was assessed at rest and 30 and 60 min after each exercise, and then the normalized FMD (nFMD) was calculated from the peak shear rate. The nFMD (a.u.) significant increased 30 min after IE (1.2 ± 0.2 to 3.0 ± 1.0, p<0.05) and increased 30 min after CE (1.0 ± 0.2 to 1.4 ± 0.2, n.s.) and returned to baseline at 60 min after both exercises, while the nFMD decreased 30 min after RE (1.3 ± 0.2 to 1.2 ± 0.1, n.s.) and was sustained at 60 min. The nFMD value at 30 min after IE was significantly greater than that at 30 min after RE (3.0 ± 1.0 versus 1.2 ± 0.1, p<0.05). These results suggest that RE may lead to a less improvement in the vascular endothelial function than CE and IE.
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Tamura et al. (2017) conducted an RCT in Healthy (n=10). Repetition exercise (RE) vs. Interval exercise (IE) and Continuous exercise (CE) was evaluated on Normalized flow-mediated vasodilation (nFMD) at 30 minutes post-exercise (p=<0.05).
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