Key result
Particulate microembolisation during carotid endarterectomy is linked to cognitive decline at six months.
Why the study?
The impact of carotid endarterectomy on cognitive function and health related quality of life was unclear.
Does carotid endarterectomy lead to a decline in cognitive function or health related quality of life in patients undergoing the procedure?
Cohort (n=109)
Does carotid endarterectomy lead to a decline in cognitive function or health related quality of life in patients undergoing the procedure?
Carotid endarterectomy may lead to cognitive decline associated with procedural microembolisation, although patients' self-reported quality of life remains stable at 6 months.
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Intraoperative microembolisation was associated with cognitive decline on select tests after CEA; leaves open whether targeted embolic protection improves neurocognitive outcomes.
Lloyd et al. (2004) conducted a cohort in Carotid endarterectomy (n=109). Carotid endarterectomy and particulate microembolisation vs. Pre-surgery baseline was evaluated on Cognitive function and health related quality of life. Particulate microembolisation during carotid endarterectomy was a significant risk factor for declining cognitive function at 6 months, though quality of life did not deteriorate.
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