Key result
CEA fails to improve cognition in asymptomatic severe carotid stenosis.
Why the study?
The relationship between carotid stenosis, cognitive deterioration, and the effects of carotid endarterectomy in asymptomatic severe carotid artery stenosis was unclear.
Does carotid endarterectomy improve cognitive performance in non-demented subjects with asymptomatic severe carotid artery stenosis?
Observational (n=60)
Does carotid endarterectomy improve cognitive performance in non-demented subjects with asymptomatic severe carotid artery stenosis?
Carotid endarterectomy does not improve cognitive performance in patients with asymptomatic severe carotid stenosis, suggesting that underlying vascular risk factors rather than the stenosis itself drive cognitive decline.
No support for CEA to improve cognition in asymptomatic carotid stenosis; leaves open whether stenosis independently affects cognition beyond vascular risks.
Cognition and the effects of carotid endarterectomy (CEA) were evaluated in 22 non-demented subjects with vascular risk factors (VRF) and asymptomatic severe carotid artery stenosis (ASCAS), 14 volunteers with VRF but without stenosis, and 24 healthy controls (HC) without VRF. Non-demented subjects with VRF, with or without carotid stenosis scored inferior to HC. It is concluded that carotid stenosis is not a primary cause of cognitive deterioration and CEA does not improve cognition in patients with ASCAS.
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Aharon‐Peretz et al. (2003) conducted an observational in Asymptomatic severe carotid artery stenosis (n=60). Carotid endarterectomy (CEA) and carotid stenosis vs. Volunteers with vascular risk factors without stenosis and healthy controls without vascular risk factors was evaluated on Cognition. Carotid endarterectomy did not improve cognition in patients with asymptomatic severe carotid artery stenosis, and carotid stenosis was not a primary cause of cognitive deterioration.
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