Key result
MSCT rules out significant CAD with ~95% negative predictive value despite low sensitivity.
Why the study?
The accuracy of multislice cardiac computed tomography for detecting significant coronary artery disease in middle-aged symptomatic women was not well established.
Does multislice cardiac computed tomography (MSCT) accurately detect significant coronary artery disease compared to coronary arteriography in symptomatic middle-aged women with an abnormal exercise ECG?
Population
70 middle-aged symptomatic women with abnormal exercise ECG
Comparison
Multislice cardiac computed tomography vs coronary arteriography
Design
Cross-sectional study with blinded comparison
Authors
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MSCT offers high NPV for ruling out significant CAD in symptomatic middle-aged women with abnormal stress tests; leaves open routine adoption pending larger prospective validation.
Cross-Sectional (n=70)
Blinded
Does multislice cardiac computed tomography (MSCT) accurately detect significant coronary artery disease compared to coronary arteriography in symptomatic middle-aged women with an abnormal exercise ECG?
MSCT is highly accurate with an excellent negative predictive value for diagnosing significant CAD in symptomatic middle-aged women with abnormal stress tests.
Shivalkar et al. (2007) conducted a cross-sectional in Coronary artery disease (n=70). Multislice cardiac computed tomography (MSCT) vs. Coronary arteriography (CA) was evaluated on Diagnostic accuracy for significant coronary artery disease. Multislice cardiac computed tomography showed high diagnostic accuracy for significant coronary artery disease, with 95% negative predictive value, 99% specificity, and 50% sensitivity.
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