Key result
Aneurysmal fibrous histiocytoma presents as a polypoid swelling with CD34-negative vascular spaces lacking endothelial lining.
Why the study?
Aneurysmal Fibrous Histiocytoma is a rare variant of Cutaneous Fibrous Histiocytoma characterized by a high rate of recurrence and distinct clinical and morphological features.
Case Report (n=1)
This case report highlights the rare aneurysmal variant of fibrous histiocytoma, characterized by vascular spaces lacking endothelial lining and negative CD34 staining, which is known for a high rate of recurrence.
Answers are grounded in this paper and cite their sources.
Include aneurysmal fibrous histiocytoma in polypoid lesion differentials; extends reported histologic spectrum in Level 5 evidence.
Aneurysmal Fibrous Histiocytoma (AFH) is a distinct and a rare clinicopathological variant of Cutaneous Fibrous Histiocytoma (CFH). It differs from the usual benign fibrous histiocytoma clinically and morphologically with high rate of recurrence. Here, we report a case of AFH with history of recurrence which presented as a polypoid swelling and showed vascular spaces with no endothelial lining which was proved negative by CD34 immunostaining. The spaces were bordered by tumour cells.
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Aniya Antony (2017) conducted a case report in Aneurysmal Fibrous Histiocytoma (n=1). A case of aneurysmal fibrous histiocytoma presented as a polypoid swelling with vascular spaces lacking endothelial lining, confirmed negative by CD34 immunostaining.
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