Key result
Mechanical AVR with intraoperative hemofiltration shows favorable outcomes and smoother post-operative hemodialysis in anuric ESRD.
Why the study?
Aortic valve dysfunction is the most prevalent valvular pathology among chronic renal disease patients receiving hemodialysis, with limited data on management in high-risk anuric ESRD patients.
Case Report (n=1)
Surgical aortic valve replacement using an intraoperative hemofilter can be successfully performed in high-risk anuric patients with ESRD on hemodialysis, improving post-operative dialysis tolerance.
Cardiovascular disease affects more than 50% of individuals receiving dialysis. Cardiac issues affect about half of dialysis patients with end-stage renal disease (ESRD). The most prevalent valvular pathology among chronic renal disease patients receiving hemodialysis is aortic valve dysfunction. This case report presented very high-risk surgery in anuria patients with favorable outcomes. Forty-six-year-old male was a known case of ESRD on hemodialysis (HD) for the last 3–4 years under the treatment of a nephrologist. He is admitted with complaints of breathlessness at rest, weakness with lethargy, occasional chest pain, and anuria. In view of his symptomatology two-dimensional echocardiography which revealed severe aortic stenosis. No Foley catheterization was done in view of anuria during surgery. The #21 mm bileaflet mechanical aortic valve prosthesis was implanted. Intraoperative hemofilter was used to manage the fluid balance (3 L ultrafiltration done during cardiopulmonary bypass). Presurgery HD used to be of relatively prolonged duration and without getting required ultrafiltration. After surgical intervention, dialysis was done smoothly, without any episodes of hypotension and HD duration is shortened.
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Sonia et al. (2025) conducted a case report in Severe aortic stenosis and end-stage renal disease (n=1). Aortic valve replacement (#21 mm bileaflet mechanical prosthesis) with intraoperative hemofiltration was evaluated on Surgical outcome and hemodialysis tolerance. Aortic valve replacement with a mechanical prosthesis and intraoperative hemofiltration in an anuric patient with ESRD resulted in favorable outcomes and smoother, shorter post-operative hemodialysis.
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