Key result
TAVI in frail patients carries ~8% 30-day mortality.
Why the study?
Frailty instruments used for TAVI recipients vary widely, leading to inconsistent frailty prevalence estimates and uncertain prognostic data.
What is the mortality rate in frail patients undergoing transcatheter aortic valve implantation?
Meta-Analysis
What is the mortality rate in frail patients undergoing transcatheter aortic valve implantation?
Frail patients undergoing TAVI have a 1-year mortality of approximately 27%, though prognostic estimates are limited by substantial heterogeneity in how frailty is measured across studies.
No takes yet. Share an insight, caveat, or question.
Frail TAVI patients carry high mortality risk; leaves open standardized frailty phenotyping to improve risk stratification.
Li et al. (2021) conducted a meta-analysis in Aortic stenosis in frail patients. Frailty (Fried or modified Fried phenotype) was evaluated on 30-day mortality (95% CI 5.20-11.70). In frail patients undergoing TAVI, pooled 30-day mortality was 7.86% (95% CI 5.20-11.70%) and 1-year mortality was 26.91% when assessed by the Fried or modified Fried phenotype.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: