December 1, 2006Pacing and Clinical Electrophysiology
Perioperative Biventricular Pacing Leads to Improvement of Hemodynamics in Patients with Reduced Left‐Ventricular Function—Interim Results
Key result
Temporary biventricular pacing increases cardiac output in ~59% of patients with severely reduced LVEF after cardiac surgery.
- n=54
Why the study?
Most studies have investigated hemodynamic effects of CRT in chronic congestive heart failure but not in postoperative heart failure after open heart surgery.
Does perioperative temporary biventricular pacing improve hemodynamics in patients with severely reduced left ventricular function undergoing open heart surgery?
Population
54 patients undergoing open heart surgery with severely reduced left ventricular function and widened QRS complexes
Comparison
Perioperative temporary biventricular pacing vs no pacing
Design
Observational cohort study
Follow-up
24 hours
Authors
Discussion
Loading...
Member takes
Implication
May benefit select post-op patients with low EF; leaves open responder identification and randomized confirmation.
Structured PICO
Does perioperative temporary biventricular pacing improve hemodynamics in patients with severely reduced left ventricular function undergoing open heart surgery?
P
Population
54 patients with severely reduced left ventricular function and widened QRS complexes undergoing open heart surgery, followed for 24 hours postoperatively.
I
Intervention
Perioperative temporary biventricular pacing via one left and one right ventricular epicardial wire
O
Outcome
Hemodynamic parameters (cardiac output) measured immediately, 6 hours, and 24 hours postoperativelysurrogate
Perioperative temporary biventricular pacing improves cardiac output in approximately 60% of patients with severely reduced left ventricular function undergoing open heart surgery.
Cite This Study
Dzemali et al. (2006) studied Reduced left-ventricular function and widened QRS complexes (n=54). Perioperative temporary biventricular pacing was evaluated on Increase in cardiac output. Perioperative temporary biventricular pacing led to an increase in cardiac output in 59.2% of patients with severely reduced left ventricular function undergoing open heart surgery.