Key result
Biventricular and targeted left ventricular pacing yielded significantly higher cardiac output than right ventricular pacing (6.7 and 6.2 vs 5.4 L/min; P≤0.001 and P≤0.05) after cardiac surgery.
Why the study?
Does RT3DE targeted LV or BIV pacing improve hemodynamic parameters compared to RV pacing in patients with LV dysfunction early after cardiac surgery?
Population
n=21 patients with ischemic or valvular heart disease and left ventricular dysfunction in the early…
Comparison
Three-dimensional echocardiography targeted left… vs Right ventricular (RV) pacing.
Design
RCT, Prospective randomized trial
Follow-up
Within 72 hours after cardiac surgery
Authors
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Supports biventricular or targeted LV pacing over RV pacing to optimize cardiac output early after cardiac surgery in LV dysfunction; extends perioperative resynchronization evidence.
RCT (n=21)
randomized
Does RT3DE targeted LV or BIV pacing improve hemodynamic parameters compared to RV pacing in patients with LV dysfunction early after cardiac surgery?
p-value: p=BIV vs RV P≤0.001; LV vs RV P≤0.05
Targeted biventricular and left ventricular pacing significantly improve cardiac output and cardiac index compared to right ventricular pacing in the early postoperative period after cardiac surgery in patients with LV dysfunction.
Straka et al. (2011) conducted an RCT in Ischemic or valvular heart disease with left ventricle dysfunction after cardiac surgery (n=21). Biventricular (BIV) and RT3DE targeted left ventricle (LV) pacing vs. Right ventricular (RV) pacing was evaluated on Cardiac output (CO) and cardiac index (CI) (p=BIV vs RV P≤0.001; LV vs RV P≤0.05). Biventricular and targeted left ventricular pacing yielded significantly higher cardiac output than right ventricular pacing (6.7 and 6.2 vs 5.4 L/min; P≤0.001 and P≤0.05) after cardiac surgery.
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