Key result
In vitro transfection of isolated myocytes from patients with dilated cardiomyopathy with an adenovirus expressing SERCA2a increased Ca2+ ATPase activity by 80% and normalized myocyte function.
Population
Isolated myocytes from patients with dilated cardiomyopathy and intact rabbit hearts
Design
Editorial
Authors
Loading...
Adenoviral gene transfer of SERCA2a or beta-2 adrenergic receptors can improve contractile function in failing cardiac myocytes and intact hearts.
Adenoviral gene transfer of SERCA2a or beta-2 adrenergic receptors can improve contractile function in failing cardiac myocytes and intact hearts.
William H. Barry (1999) conducted an editorial in Dilated cardiomyopathy. Adenovirus expressing SERCA2a was evaluated on Ca2+ ATPase activity. In vitro transfection of isolated myocytes from patients with dilated cardiomyopathy with an adenovirus expressing SERCA2a increased Ca2+ ATPase activity by 80% and normalized myocyte function.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: