Key result
Polycystic ovary syndrome was associated with non-alcoholic fatty liver disease in young females, with 46% of PCOS patients exhibiting fatty liver compared to 32% of those without PCOS.
Why the study?
Is polycystic ovary syndrome associated with non-alcoholic fatty liver disease in young females?
Cross-Sectional (n=272)
No
Is polycystic ovary syndrome associated with non-alcoholic fatty liver disease in young females?
This study highlights a significant prevalence of non-alcoholic fatty liver disease among young females with polycystic ovary syndrome, suggesting a need for metabolic screening in this population.
Answers are grounded in this paper and cite their sources.
PCOS associated with NAFLD on ultrasound in young females; hypothesis-generating and should not yet change practice.
PCOS and nonalcoholic fatty liver disease are both associated with the metabolic syndrome, which is characterized by central adiposity, hypertension, diabetes, and dyslipidemia. Objective: To determine the association between poly cystic ovaries and non-alcoholic fatty liver disease in young females. Methods: In this cross-sectional study at Chughtai Medical Center in Lahore, 272 patients with polycystic ovaries and fatty liver disease were selected. Utilizing a convex abdominal instrument with a frequency range of 3-5 MHz, the Toshiba Nemio 17 was utilized. Results: In this study, 74 out of 272 female patients diagnosed with PCOS also had fatty liver, highlighting a significant association (p-value = 0.025). Notably, within the 17-25 age group, 45 to 46 patients exhibited fatty liver, suggesting a link between PCOS and fatty liver in younger individuals experiencing hormonal issues. Conclusions: This study demonstrates association between polycystic ovary syndrome in adolescent females and with nonalcoholic fatty liver disease. The findings support the notion that PCOS is more prevalent in individuals with NAFLD.
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Malik et al. (2023) conducted a cross-sectional in Polycystic ovary syndrome and non-alcoholic fatty liver disease (n=272). Polycystic ovary syndrome vs. Females without polycystic ovary syndrome was evaluated on Presence of fatty liver on ultrasound (p=0.025). Polycystic ovary syndrome was associated with non-alcoholic fatty liver disease in young females, with 46% of PCOS patients exhibiting fatty liver compared to 32% of those without PCOS.
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