Key result
EBV-induced primary cardiac lymphoma in a heart allograft manifests as refractory electrical storm.
Why the study?
Lymphomas are a significant cause of morbidity and mortality after heart transplantation, with primary cardiac lymphoma on the graft being highly rare and challenging to manage.
Case Report (n=1)
Primary cardiac lymphoma on a transplanted heart graft is a rare complication that can present as an electrical storm and carries a poor prognosis.
Answers are grounded in this paper and cite their sources.
Alerts clinicians to EBV-related cardiac lymphoma in post-transplant electrical storm; leaves open optimal surveillance and management strategies.
Background: Cancers, and specifically lymphomas, are one of the main causes of morbidity and mortality after heart transplantation. Sixteen percent of heart transplant recipients develop cancer within 5 years and lymphomas represent 10% of these patients. Case summary: We report the case of an Epstein-Barr Virus-induced primary cardiac lymphoma on the graft. The patient initially present an electrical storm quickly controlled under medical treatment. The multimodal exploration led us to the diagnosis of lymphoma. The lymphoma has spread quickly in spite of the numerous treatments we have tried and has resulted in arrhythmia complications. Discussion: This case report highlights the challenging management of heart transplant lymphoma and its treatment. Primary cardiac lymphoma on the graft is highly rare with poor prognosis and arrhythmia complications.
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Charbonneau et al. (2022) conducted a case report in Epstein-Barr Virus-induced primary cardiac lymphoma on a transplanted heart (n=1). Medical treatment for lymphoma and electrical storm was evaluated on Clinical course and arrhythmia complications. An Epstein-Barr Virus-induced primary cardiac lymphoma on a heart graft presented as an electrical storm and spread rapidly despite numerous treatments, resulting in arrhythmia complications.
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