Key result
Nurse-led GDMT titration cuts all-cause hospitalizations and improves survival in HFrEF.
Why the study?
The impact of nurse-led titration of β-adrenergic blockers, ACE inhibitors, and ARBs on outcomes in patients with HFrEF was evaluated.
Does nurse-led titration of β-adrenergic blocking agents, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers in patients with heart failure with reduced ejection fraction improve outcomes?
Does nurse-led titration of β-adrenergic blocking agents, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers in patients with heart failure with reduced ejection fraction improve outcomes?
Answers are grounded in this paper and cite their sources.
Nurse-led titration of heart failure medications improves survival, reduces hospitalizations, and accelerates target dose achievement in HFrEF patients.
Clinical Question: Does nurse-led titration of β-adrenergic blocking agents, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers in patients with heart failure with reduced ejection fraction improve outcomes? Bottom Line: Participants whose treatment included nurse-led titration experienced fewer hospital admissions for any cause and an increase in survival, with more participants reaching target dose within a shorter period.
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Driscoll et al. (2016) conducted a review in Heart failure with reduced ejection fraction. Nurse-led titration of β-adrenergic blocking agents, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers was evaluated on Hospital admissions for any cause and survival. Nurse-led titration of beta-blockers, ACE inhibitors, and ARBs in patients with HFrEF resulted in fewer hospital admissions for any cause and an increase in survival.
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