Key result
A nurse-directed GDMT titration program significantly increased the mean number of guideline-directed medical therapies at target doses from 0.54 to 1.52 (p < 0.001).
Why the study?
Does a dedicated nursing-led GDMT clinic improve the proportion of HFrEF patients on target doses of guideline-directed medical therapy?
Population
61 patients with heart failure with reduced ejection fraction referred to a focused GDMT clinic at a single…
Design
Cohort
Follow-up
Mean 264.44 ± 162.68 days
Authors
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Low GDMT uptake (<25%) in HFrEF demands immediate implementation efforts; confirms persistent guideline-practice gap requiring targeted research.
Observational (n=61)
No
Does a dedicated nursing-led GDMT clinic improve the proportion of HFrEF patients on target doses of guideline-directed medical therapy?
Absolute Event Rate: 1.52% vs 0.54%
p-value: p=<0.001
A dedicated nursing-led GDMT titration clinic significantly improves the proportion of HFrEF patients achieving target medication doses and is associated with improved ejection fraction and reduced hospitalizations.
Balakumaran et al. (2018) conducted an observational in Heart failure with reduced ejection fraction (n=61). Dedicated nursing led guideline directed medical therapy (GDMT) clinic vs. Prior to initial encounter (baseline) was evaluated on Mean number of GDMT at target doses (p=<0.001). A nurse-directed GDMT titration program significantly increased the mean number of guideline-directed medical therapies at target doses from 0.54 to 1.52 (p < 0.001).
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