Key result
4D flow MRI strongly correlates with invasive pressure gradients post-TIPS with an r of ~0.94.
Why the study?
Post-TIPS portosystemic pressure gradient measurement is invasive, motivating development of reliable noninvasive alternatives for longitudinal monitoring.
Does noninvasive assessment using 4D flow MRI and CT-based CFD accurately estimate post-TIPS portosystemic pressure gradient compared to invasive measurement in post-TIPS patients?
Observational (n=31)
Does noninvasive assessment using 4D flow MRI and CT-based CFD accurately estimate post-TIPS portosystemic pressure gradient compared to invasive measurement in post-TIPS patients?
Effect estimate: r=0.94
p-value: p=<0.01
4D flow MRI-derived relative pressure mapping provides a highly accurate noninvasive estimation of post-TIPS portosystemic pressure gradient, offering a potential alternative to invasive monitoring.
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Supports noninvasive post-TIPS PPG estimation by 4D flow MRI; leaves open prospective validation before clinical adoption.
Chen et al. (2026) conducted an observational in Post-transjugular intrahepatic portosystemic shunt (TIPS) (n=31). 4D flow MRI and CT-based CFD vs. Invasively measured PPG was evaluated on Correlation and agreement with invasively measured PPG (r=0.94, p=<0.01). Noninvasive estimation of post-TIPS portosystemic pressure gradient using 4D flow MRI correlated strongly with invasive measurements (r=0.94, P<0.01) and showed excellent agreement.
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