Key result
Adenosine/thallium imaging is linked to low false-positive septal defect rates of at most ~4% in LBBB.
Why the study?
The exercise 201Tl imaging procedure in patients with LBBB is associated with a relatively high frequency of false-positive septal perfusion defects, prompting evaluation of adenosine/thallium imaging.
What is the frequency of false-positive septal defects on adenosine/thallium imaging in patients with left bundle branch block?
Population
68 patients with LBBB on resting ECG undergoing adenosine/thallium imaging
Comparison
Adenosine/thallium imaging vs exercise/thallium imaging
Design
Observational study reviewing 900 adenosine/thallium cases
Authors
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Adenosine/thallium imaging shows low false-positive septal defects in LBBB; supports further study as alternative but should not yet change practice.
Observational (n=68)
No
What is the frequency of false-positive septal defects on adenosine/thallium imaging in patients with left bundle branch block?
Adenosine/thallium imaging is associated with a low frequency of false-positive septal defects in patients with LBBB and is a viable alternative to exercise/thallium imaging.
Patel et al. (1995) conducted an observational in Left bundle branch block (n=68). Adenosine/thallium imaging was evaluated on False-positive reversible septal defects. Adenosine/thallium imaging in patients with left bundle branch block was associated with a low frequency of false-positive reversible septal defects (at most 4%).
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