Key result
Adenosine thallium imaging yields ~4% false-positive reversible septal defects in LBBB.
Why the study?
The exercise 201Tl imaging procedure in patients with LBBB is associated with a relatively high frequency of false-positive septal perfusion defects, prompting evaluation of adenosine/thallium imaging.
What is the frequency of false-positive septal defects on adenosine/thallium imaging in patients with left bundle branch block?
Population
68 patients with LBBB on resting ECG undergoing adenosine/thallium imaging
Comparison
Adenosine/thallium imaging vs exercise/thallium imaging
Design
Observational cohort study reviewing 900 adenosine/thallium cases
Authors
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Low false-positive rate supports consideration of adenosine/thallium in LBBB; leaves open need for randomized validation.
Observational (n=68)
No
What is the frequency of false-positive septal defects on adenosine/thallium imaging in patients with left bundle branch block?
Adenosine/thallium imaging is associated with a low frequency of false-positive septal defects in patients with LBBB, supporting its use as an alternative to exercise imaging in this population.
Patel et al. (1995) conducted an observational in Left bundle branch block (LBBB) (n=68). Adenosine/thallium imaging was evaluated on Frequency of false-positive reversible septal defects. Adenosine/thallium imaging in patients with left bundle branch block demonstrated a low frequency of false-positive reversible septal defects (at most 4%).
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