Key result
A longer time interval from symptom onset to appendectomy was significantly associated with a higher pathology grade (p=0.01) and an increased rate of postoperative complications.
Why the study?
Does the time from symptom onset to appendectomy correlate with pathology grade and complications in adults with acute appendicitis?
Population
171 adult patients who underwent emergent appendectomy for acute appendicitis
Design
Cohort
Authors
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Delays from symptom onset to appendectomy were associated with advanced pathology and complications; supports early intervention but leaves causality and practice change open pending randomized data.
Observational (n=171)
No
Does the time from symptom onset to appendectomy correlate with pathology grade and complications in adults with acute appendicitis?
Absolute Event Rate: 63% vs 42.29%
p-value: p=0.01
Longer time from symptom onset to appendectomy correlates with increased pathology grade and complication rates, supporting the recommendation for early appendectomy.
Foul et al. (2019) conducted an observational in Acute appendicitis (n=171). Prolonged time from symptom onset to surgery (Total Interval) vs. Shorter time from symptom onset to surgery was evaluated on Correlation between time from symptom onset to surgery (total interval) and pathology grade (p=0.01). A longer time interval from symptom onset to appendectomy was significantly associated with a higher pathology grade (p=0.01) and an increased rate of postoperative complications.
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