Key result
Nonopioid-based general anesthesia was as effective as opioid-based anesthesia for bariatric surgery, with no statistically significant differences in hemodynamics across eight time points.
Why the study?
Does non-opioid based general anesthesia improve hemodynamics and pain compared to opioid based anesthesia in obese patients undergoing bariatric surgery?
Population
Obese patients (body mass index >50 Kg/m2) undergoing laparoscopic sleeve gastrectomies
Comparison
Non-opioid based general anesthesia vs Opioid based general anesthesia
Design
RCT, Computer generated randomization table, Double-blind
Follow-up
24 hours
Authors
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Supports opioid-sparing anesthesia in bariatric surgery; reinforces RCT evidence for nonopioid regimens in obese patients.
RCT
Double-blind
Computer generated randomization table
Does non-opioid based general anesthesia improve hemodynamics and pain compared to opioid based anesthesia in obese patients undergoing bariatric surgery?
Non-opioid based general anesthesia is as effective as opioid-based anesthesia for bariatric surgery, with a trend toward less pain.
Mansour et al. (2013) conducted an RCT in Obesity requiring bariatric surgery. Nonopioid based general anesthesia vs. Opioid based general anesthesia was evaluated on Hemodynamics (heart rate, systolic, diastolic, and mean arterial blood pressure) and pain monitoring (VAS). Nonopioid-based general anesthesia was as effective as opioid-based anesthesia for bariatric surgery, with no statistically significant differences in hemodynamics across eight time points.
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