Key result
Insulin resistance in PCOS is linked to ~10% higher serum uric acid levels.
Why the study?
Females with polycystic ovarian syndrome have multiple cardiovascular risk factors including insulin resistance and may have abnormal uric acid profiles, but uric acid levels in PCOS with and without insulin resistance have not been compared.
Are uric acid levels higher in females with PCOS and insulin resistance compared to those without insulin resistance?
Population
108 females with PCOS divided into insulin resistance (54) and non-insulin resistance (54) groups
Comparison
PCOS with insulin resistance vs PCOS without insulin resistance
Design
Cross-sectional comparative study
Authors
Loading...
May signal added CV risk in PCOS with IR; leaves open whether it predicts outcomes or warrants intervention.
Cross-Sectional (n=108)
No
Are uric acid levels higher in females with PCOS and insulin resistance compared to those without insulin resistance?
Absolute Event Rate: 4.92% vs 4.48%
p-value: p=<0.05
Females with PCOS and insulin resistance have significantly higher uric acid levels compared to those without insulin resistance, highlighting a potential additional cardiovascular risk factor.
Riaz et al. (2023) conducted a cross-sectional in Polycystic ovarian syndrome (n=108). Insulin resistance vs. PCOS without insulin resistance was evaluated on Serum uric acid level (mg/dl) (p=<0.05). Women with polycystic ovarian syndrome and insulin resistance had significantly higher mean serum uric acid levels compared to those without insulin resistance (4.92 vs 4.48 mg/dl, p<0.05).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: