Key result
The AMPD1 exon 2 T34 allele frequency was significantly lower in elite Polish power-oriented athletes compared with controls (5.38% vs 13.13%; P=0.0007).
Why the study?
Does the AMPD1 C34T polymorphism associate with elite power-oriented athlete status in Polish males?
Case-Control (n=318)
Does the AMPD1 C34T polymorphism associate with elite power-oriented athlete status in Polish males?
Absolute Event Rate: 5.38% vs 13.13%
p-value: p=0.0007
The AMPD1 exon 2 T34 allele is less frequent in elite Polish power-oriented athletes, suggesting the C allele may be advantageous for attaining elite status in power-oriented sports.
Authors
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AMPD1 genotype differences may link to power athlete status; hypothesis-generating and should not yet guide selection or training.
Cięszczyk et al. (2011) conducted a case-control in Power-oriented athlete status (n=318). AMPD1 C34T polymorphism vs. Unrelated male volunteers was evaluated on AMPD1 exon 2 T34 allele frequency (p=0.0007). The AMPD1 exon 2 T34 allele frequency was significantly lower in elite Polish power-oriented athletes compared with controls (5.38% vs 13.13%; P=0.0007).
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