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May 16, 2025JACC Case ReportsOpen Access

Leadless Atrial Pacing Targeting Bachmann's Bundle for Atrial Resynchronization

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Key result

Leadless atrial pacing targeting Bachmann's bundle was successfully implanted in a 49-year-old woman, reducing right atrium-to-lateral left atrium conduction time and paced P wave duration.

Why the study?

Does leadless atrial pacing targeting Bachmann's bundle improve atrial resynchronization in a patient with sinus node dysfunction and interatrial conduction delay?

Population

49-year-old woman with sinus node dysfunction and interatrial conduction delay (n=1)

Design

Case_report

Authors

ZHZachary HollisEYEunice YangKRKyungmoo Ryu

Discussion

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Member takes

Overview

Feasibility of leadless BBAP in one case is hypothesis-generating; leaves open efficacy, safety, and role in atrial resynchronization.

Study Design

Type

Case Report (n=1)

Structured PICO

Does leadless atrial pacing targeting Bachmann's bundle improve atrial resynchronization in a patient with sinus node dysfunction and interatrial conduction delay?

P
Population
A 49-year-old woman with sinus node dysfunction and interatrial conduction delay.
I
Intervention
Leadless atrial pacemaker targeting Bachmann's bundle (BBAP) guided by intracardiac echocardiography and electrographic mapping
O
Outcome
Right atrium-to-lateral left atrium conduction time and paced P wave durationsurrogate

This first-in-human case demonstrates the feasibility of leadless Bachmann's bundle area pacing to achieve atrial resynchronization, potentially offering a more physiological approach than traditional right atrial appendage pacing.

Cite This Study

Hollis et al. (2025) conducted a case report in Sinus node dysfunction and interatrial conduction delay (n=1). Leadless atrial pacemaker targeting Bachmann's bundle was evaluated on Right atrium-to-lateral left atrium conduction time and paced P wave duration. Leadless atrial pacing targeting Bachmann's bundle was successfully implanted in a 49-year-old woman, reducing right atrium-to-lateral left atrium conduction time and paced P wave duration.

synapsesocial.com/papers/6ab368373550cfb2c045d0f9https://doi.org/10.1016/j.jaccas.2025.104083
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevention of Chronic Atrial Fibrillation by Pacing in the Region of Bachmann's Bundle: Results of a Multicenter Randomized Trial2001 · 279 citations
  2. 2Clinical impact of Bachmann’s bundle pacing defined by electrocardiographic criteria on atrial arrhythmia outcomes2022 · 70 citations
  3. 3P‐wave and interatrial block: New predictor for atrial high rate episodes in patients with cardiac implantable electronic devices2018 · 22 citations
  4. 4Interatrial Block in the Modern Era2014 · 84 citations