Key result
LMWH enables successful pregnancy in a patient with Buerger's disease.
Why the study?
The association between pregnancy and Buerger's disease is rare and its management during gestation is not well described.
Case Report (n=1)
Low-molecular-weight heparin may be a viable treatment option for managing Buerger's disease during pregnancy to achieve successful maternal and fetal outcomes.
Pregnancy-associated Buerger's case may prompt tobacco cessation emphasis in young women; leaves open causal link pending larger cohorts.
Buerger's disease (BD), also known as thromboangiitis obliterans, is a non-atherosclerotic inflammatory disorder of unknown aetiology that affects small-sized and medium-sized vessels of the extremities. It is usually observed in middle-aged adults, especially those who smoke or use tobacco products. This condition is more frequently observed in men, although recent findings indicate an increasing prevalence among women, potentially due to increased cigarette use. The association between pregnancy and BD is rare, with only a few published cases. Previous reports have indicated that BD may worsen during gestation due to the characteristic hypercoagulable state of pregnancy. In addition, it seems to be associated with intrauterine growth restriction secondary to infarction of placental vessels. Careful obstetric management of maternal and fetal status is mandatory in pregnancies complicated with BD. We report a successful case of a pregnancy in a patient with BD treated with low-molecular-weight heparin.
No takes yet. Share an insight, caveat, or question.
Silva et al. (2023) conducted a case report in Buerger's disease during pregnancy (n=1). Low-molecular-weight heparin was evaluated on Successful pregnancy. Treatment with low-molecular-weight heparin resulted in a successful pregnancy in a patient with Buerger's disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: