Key result
A 22-year-old pregnant woman with no history of tobacco use developed Buerger's disease with dry gangrene, which was managed with medical therapy and cesarean delivery at 37 weeks.
Why the study?
Buerger's disease is sporadic in young women, presenting a rare diagnostic and therapeutic dilemma in a pregnant woman with gangrene and no history of tobacco addiction.
Case Report (n=1)
Buerger's disease can rarely present in pregnant women without a history of tobacco use, likely triggered by the hypercoagulable state of pregnancy, and can be managed medically to halt gangrene progression.
May support medical limb salvage in rare Buerger's cases during pregnancy; leaves open optimal therapy and fetal risks.
Thromboangitis obliterans or Buerger's disease is a segmental inflammatory condition of small and medium-sized arteries and veins. It is commonly seen in males with age under 45 years and with a current or recent history of tobacco use, and in smokers. It is sporadic in young women. This report describes a primigravida with dry gangrene in both upper and lower limbs because of Buerger's disease. The primary diagnosis of the disease occurred first time in pregnancy at the 17th week of gestation with the patient reporting dry gangrene and pain in the digits and confirmed with a non-invasive Doppler study. The patient was screened for autoimmune diseases, diabetes mellitus, and the presence of hypercoagulable disorders. Echocardiography and arteriography were performed to rule out any source of emboli. The case report aims to discuss a rare diagnostic and therapeutic dilemma in the case of a pregnant woman presenting with gangrene without any history of tobacco addiction.
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Karena et al. (2022) conducted a case report in Buerger's disease (Thromboangiitis obliterans) (n=1). Medical management and cesarean section was evaluated on Clinical improvement and pregnancy outcome. A 22-year-old pregnant woman with no history of tobacco use developed Buerger's disease with dry gangrene, which was managed with medical therapy and cesarean delivery at 37 weeks.
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