Key result
NAFLD is linked to altered LVMI and hypertrophy risk in obese children.
Why the study?
No reported study has analyzed the relationship between NAFLD and the Left Ventricle Mass Index in obese children.
Is non-alcoholic fatty liver disease associated with an increased left ventricle mass index in obese children?
Cross-Sectional (n=146)
No
Is non-alcoholic fatty liver disease associated with an increased left ventricle mass index in obese children?
This study investigates the potential association between non-alcoholic fatty liver disease and left ventricular hypertrophy in obese children.
Answers are grounded in this paper and cite their sources.
NAFLD may associate with higher LVMI in children; hypothesis-generating and requires longitudinal confirmation before clinical relevance.
alcoholic fatty liver diseaseLeft Ventricular Hypertrophy (LVH) has prognostic importance in adults and is generally considered to have a similar prognostic value in children.Numerous population-based and hypertensive cohort studies investigating the impact of adiposity on left ventricle structure have shown that LVH is more prevalent in obese individuals than in their lean counterparts [7,8].No reported study has analyzed the relationship between NAFLD and the Left Ventricle Mass Index (LVMI) in obese children.Thus, this study investigated the risk factors for left ventricle hypertrophy and determined the relationship between NAFLD and the LVMI in obese children. Material and MethodsThis was a cross-sectional study that included 98 obese children and 48 age-and gender-matched non-obese children as a control group.Subjects were enrolled randomly from among the obese children admitted to the Pediatric Endocrinology Department of Ankara Research and Training Hospital.To compare variables that differed significantly between the obese children and controls, the obese children were subdivided into two groups according to the presence of NAFLD.
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Beray Selver (2012) conducted a cross-sectional in Obesity and Non-Alcoholic Fatty Liver Disease (n=146). Non-Alcoholic Fatty Liver Disease (NAFLD) vs. Obese children without NAFLD and non-obese children was evaluated on Left Ventricle Mass Index (LVMI).
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