Key result
Major ECG abnormalities occur in ~91% of patients with newly diagnosed heart failure.
Why the study?
The Heart of Soweto study is examining the pattern of cardiovascular disease in Soweto, South Africa, including ECG abnormalities in heart failure patients.
What is the prevalence and pattern of ECG abnormalities in black Africans with newly diagnosed heart failure?
Cross-Sectional (n=756)
Blinded reviewers for ECG analysis
No
What is the prevalence and pattern of ECG abnormalities in black Africans with newly diagnosed heart failure?
A 12-lead ECG reveals major abnormalities in 91% of newly diagnosed heart failure patients in a South African cohort, highlighting its utility as a practical screening tool in low-income communities.
High ECG abnormality rates in Soweto HF patients affirm diagnostic utility; leaves open whether ECG screening improves outcomes in similar low-resource settings.
Background: The “Heart of Soweto” study is currently examining the pattern of cardiovascular disease (CVD) in Soweto, South Africa. Methods: As part of a large clinical registry of CVD patients presenting to the Chris Hani Baragwanath Hospital in Soweto, a 12-lead ECG was performed on 91% of “de novo” cases in 2006. Systematic analysis of the ECGs of heart failure patients was performed using detailed Minnesota coding. Results: A total of 756 de novo patients with HF (57% women, 88% Black African and mean age of 55 ± 16 years) had a 12-lead ECG. Overall, a major ECG abnormality was detected in 91% of cases consisting of ST segment changes, T wave changes, bundle branch blocks and arrhythmias. Minor abnormalities were noted in 97% of ECGs, such as axis deviation and high amplitude R waves. Left ventricular hypertrophy was evident in 15% (22% in those with a dilated cardiomyopathy) and a bundle branch block in 8% of ECGs (11% in those with an ischemic cardiomyopathy). Conclusion: Detailed examination of 12-lead ECGs of a large group of previously undiagnosed patients with HF in the Heart of Soweto study revealed many identifiable abnormalities. In addition to reconfirming the clinical utility of this cheap and practical diagnostic tool, these data highlight its potential role in screening for heart disease, particularly in low income communities.
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Lee et al. (2017) conducted a cross-sectional in Heart failure (n=756). Heart failure was evaluated on Prevalence of major ECG abnormalities. Among 756 predominantly black African patients with newly diagnosed heart failure, 12-lead ECG revealed major abnormalities in 91% and minor abnormalities in 97% of cases.
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