Key result
TEER reduces severe mitral regurgitation to trace with a 3 mm Hg gradient in cor triatriatum sinistrum.
Why the study?
The coexistence of cor triatriatum sinistrum with severe degenerative mitral regurgitation in older adults is exceptionally rare and poses technical challenges for transcatheter interventions.
Is transcatheter edge-to-edge mitral valve repair feasible and safe in a patient with severe degenerative mitral regurgitation and coexisting cor triatriatum sinistrum?
Case Report (n=1)
Is transcatheter edge-to-edge mitral valve repair feasible and safe in a patient with severe degenerative mitral regurgitation and coexisting cor triatriatum sinistrum?
This case demonstrates that transcatheter edge-to-edge mitral valve repair is feasible and safe in patients with severe degenerative mitral regurgitation and coexisting cor triatriatum sinistrum.
BACKGROUND: Cor triatriatum sinistrum (CTS) is a rare congenital malformation, and its coexistence with degenerative mitral regurgitation (MR) in older adults is exceptionally rare and creates substantial technical challenges for transcatheter interventions. CASE SUMMARY: We report a 78-year-old woman presenting with progressive dyspnea, palpitations, and lower limb edema secondary to severe MR caused by posterior mitral leaflet prolapse. Preprocedural imaging incidentally identified a complete, nonfenestrated CTS membrane. Three clips were sequentially implanted at the prolapse site, downgrading MR from severe to trace. The final mean transmitral gradient was 3 mm Hg. The patient achieved rapid symptom resolution and was discharged 7 days postprocedure. DISCUSSION: This case establishes the feasibility of mitral transcatheter edge-to-edge repair in patients with CTS through meticulous preprocedural planning and controlled transmembranous access. It broadens the therapeutic landscape for anatomically complex, surgically prohibitive older adults with valvular disease. TAKE-HOME MESSAGE: The mitral transcatheter edge-to-edge repair is feasible and safe in MR with CTS.
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Li et al. (2026) conducted a case report in Severe degenerative mitral regurgitation with coexisting cor triatriatum sinistrum (n=1). Transcatheter edge-to-edge mitral valve repair was evaluated on Mitral regurgitation severity and transmitral gradient. Transcatheter edge-to-edge mitral valve repair successfully downgraded severe mitral regurgitation to trace with a final transmitral gradient of 3 mm Hg in a patient with cor triatriatum sinistrum.
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