Key result
Preeclampsia is linked to diastolic dysfunction in ~21% of patients versus none in normotensive controls.
Why the study?
There is paucity of data on cardiac diastolic dysfunction in women with preeclampsia and its correlation with severity of the condition.
Is preeclampsia associated with cardiac diastolic dysfunction in nulliparous women?
Comparison
Women with preeclampsia vs normotensive pregnant women
Design
Case-control study with Doppler echocardiography assessment
Authors
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Preeclampsia may link to diastolic dysfunction; hypothesis-generating for screening, needs prospective validation before practice change.
Case-Control (n=150)
Is preeclampsia associated with cardiac diastolic dysfunction in nulliparous women?
Absolute Event Rate: 20.8% vs 0%
Preeclampsia is associated with a significant incidence of cardiac diastolic dysfunction, the severity of which correlates with the severity of the hypertensive disorder.
Tanuja Muthyala (2016) conducted a case-control in Preeclampsia (n=150). Preeclampsia vs. Normotensive pregnancy was evaluated on Cardiac diastolic dysfunction. Cardiac diastolic dysfunction occurred in 20.8% of women with preeclampsia compared to 0% of normotensive controls, and the grade of dysfunction correlated with preeclampsia severity (p=0.001).
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