August 1, 2004The Medical Journal of Australia
Peripheral arterial disease: prognostic significance and prevention of atherothrombotic complications
Key result
PAD is linked to a ~4-fold higher risk of 10-year mortality.
Why the study?
Peripheral arterial disease is common in people over 55, often asymptomatic, and carries a high risk of cardiovascular death comparable to coronary or cerebrovascular disease, necessitating better understanding of its prognostic significance and prevention strategies.
Population
People aged over 55 years with peripheral arterial disease
Design
Review
Authors
Discussion
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Implication
PAD confers CV mortality risk equivalent to coronary disease; leaves open whether routine ABPI screening alters outcomes in asymptomatic adults.
Structured PICO
P
Population
People aged over 55 years with peripheral arterial disease (PAD)
Peripheral arterial disease is a strong independent predictor of cardiovascular morbidity and mortality, necessitating medical management to prevent atherothrombotic complications, though routine population screening with ABPI is not currently recommended.
Limitations
- Insufficient data to recommend routine population screening for asymptomatic PAD using the ABPI
Cite This Study
Norman et al. (2004) conducted a review in Peripheral arterial disease (PAD). Peripheral arterial disease vs. No peripheral arterial disease was evaluated. Peripheral arterial disease is associated with a four-fold increased risk of death within 10 years compared to patients without the disease.