Key result
Severe COVID-19 autopsy series reveals lymphocytic myocarditis, coronaritis, and microvascular thrombosis in 100% of cases.
Why the study?
The possibility of developing lymphocytic myocarditis as part of COVID-19 in patients with severe coronavirus pneumonia remained unsubstantiated.
Population
5 elderly patients with severe COVID-19 and bilateral polysegmental pneumonia
Design
Observational postmortem case series with immunohistochemical analysis
Authors
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May indicate lymphocytic myocarditis in fatal COVID-19; hypothesis-generating for prevalence and clinical relevance.
Observational (n=5)
Yes
Postmortem analysis confirms that severe COVID-19 can cause lymphocytic viral myocarditis, often accompanied by coronaritis and microvascular thrombosis, which may be clinically missed or misdiagnosed as acute myocardial infarction.
Коган et al. (2020) conducted an observational in COVID-19 (n=5). Severe COVID-19 was evaluated on Signs of lymphocytic myocarditis. Postmortem examination of 5 patients with severe COVID-19 revealed signs of lymphocytic viral myocarditis, coronaritis, and microvascular thrombosis in all cases.
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