Key result
COVID-19 infection can cause lymphocytic pancarditis characterized by concurrent coronaritis and endopericarditis.
Why the study?
Lymphocytic viral myocarditis in COVID-19 patients was not morphologically and immunohistochemically confirmed before.
Case Report (n=4)
Autopsy findings confirm that lymphocytic viral myocarditis can occur in elderly patients with COVID-19, often accompanied by coronaritis and endo-/pericarditis.
Myocarditis in COVID-19 autopsies warrants clinical vigilance; leaves open prevalence, mechanisms, and management in larger cohorts.
The paper describes 4 autopsy cases of myocarditis in elderly patients with confirmed coronavirus infection. It gives the data of a morphological study of heart specimens and a detailed characterization of a myocardial infiltrate. An immunohistochemical study with cellular infiltrate typing was performed. The fact that lymphocytic viral myocarditis can develop in COVID-19 was morphologically and immunohistochemically confirmed. The features of myocarditis in COVID-19 are the development of the former in the presence of coronaritis and the possibility of its concurrence with lymphocytic endo- and pericarditis.
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Коган et al. (2020) conducted a case report in COVID-19 and myocarditis (n=4). COVID-19 infection was evaluated on Morphological and immunohistochemical features of myocarditis. COVID-19 infection can lead to lymphocytic viral myocarditis, which is characterized by the presence of coronaritis and concurrent lymphocytic endo- and pericarditis.
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