Key result
Electromechanical dyssynchrony affects 93% of pediatric patients after tetralogy of Fallot repair, suggesting pulmonary valve replacement alone may be insufficient for cardiac remodeling.
Why the study?
Does right ventricular resynchronization improve right and left ventricular remodeling in patients with corrected tetralogy of Fallot?
Does right ventricular resynchronization improve right and left ventricular remodeling in patients with corrected tetralogy of Fallot?
Highlights the potential role of right ventricular resynchronization in addressing electromechanical dyssynchrony and RV dysfunction in patients with corrected tetralogy of Fallot.
Many patients with corrected tetralogy of Fallot (TOF) suffer from right ventricular (RV) dysfunction during long-term follow-up. Besides a chronic pressure or volume overload caused by pulmonary regurgitation or stenosis, electromechanical dyssynchrony due to right bundle branch block (RBBB), may represent an incompletely understood cause for RV dysfunction. Hui and colleagues1 noted a dyssynchrony in 93% of pediatric patients after repair of the TOF. In these patients a pulmonary valve replacement may not be sufficient for cardiac remodeling.
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Markel et al. (2019) conducted an editorial in corrected tetralogy of Fallot (TOF). Right ventricular resynchronization was evaluated. Electromechanical dyssynchrony affects 93% of pediatric patients after tetralogy of Fallot repair, suggesting pulmonary valve replacement alone may be insufficient for cardiac remodeling.
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