Key result
Temporary RV CRT improves RV mechanics and decreases QRS duration in congenital heart disease.
Why the study?
Electromechanical discoordination may contribute to long-term pulmonary right ventricular dysfunction in patients after surgery for congenital heart disease, but effects of RV cardiac resynchronization therapy are not well characterized.
Does temporary RV cardiac resynchronization therapy improve RV mechanics and synchrony in patients with congenital heart disease and right bundle branch block?
Does temporary RV cardiac resynchronization therapy improve RV mechanics and synchrony in patients with congenital heart disease and right bundle branch block?
p-value: p=<0.001
Temporary RV cardiac resynchronization therapy acutely improves RV mechanics, synchrony, and contraction efficiency in congenital heart disease patients with right bundle branch block.
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Acute RV CRT effects in CHD with RBBB merit prospective trials; leaves open durability and clinical outcomes.
Janoušek et al. (2017) studied Congenital heart disease with complete right bundle branch block (n=25). Temporary RV cardiac resynchronization therapy vs. Baseline (spontaneous ventricular depolarization) was evaluated on Changes in RV function and mechanics (including QRS duration, RV filling time, and RV maximum +dP/dt) (p=<0.001). Temporary RV cardiac resynchronization therapy significantly decreased QRS duration (P<0.001) and improved RV mechanics and contraction efficiency in patients with congenital heart disease.
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