Key result
Circle of Willis CFD model demonstrates dynamic efferent flow and collateral recruitment in balanced configurations.
Why the study?
The application of computational fluid dynamics to model biological flows, including cerebral auto-regulation and detection of smaller arteries, is a recent development.
Computational fluid dynamics can effectively model auto-regulation in the cerebral circulation and help detect smaller arteries missed by non-intrusive MR imaging.
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CFD models enable Circle of Willis auto-regulation simulation; leaves open clinical validation for detecting smaller arteries.
David et al. (2003) studied Cerebrovascular circulation. Computational fluid dynamics (CFD) model was evaluated on Time-varying mass flow in efferent vessels and detection of smaller arteries. A computational fluid dynamics model of the Circle of Willis demonstrated time-varying mass flow in efferent vessels and the use of collateral vessels in naturally balanced configurations.
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