Key result
Suppression of humoral immunity by neonatal cyclophosphamide treatment or surgical bursectomy prevents transient paralysis caused by Marek's disease virus in chickens.
Suppression of humoral immunity prevents transient paralysis in chickens infected with Marek's disease virus, suggesting an antibody-mediated pathogenesis.
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Suggests B-cell role in MDV paralysis; leaves open relevance to other species or human viral neuropathies.
Parker et al. (1983) studied Transient paralysis caused by Marek's disease virus. Immunosuppression by neonatal cyclophosphamide (CY) treatment or surgical bursectomy (BX) was evaluated on Transient paralysis. Suppression of humoral immunity by neonatal cyclophosphamide treatment or surgical bursectomy prevents transient paralysis caused by Marek's disease virus in chickens.
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