Key result
Intravenous atropine triggers polymorphic ventricular tachycardia in a patient with unexplained recurrent syncope.
Why the study?
Atropine-induced polymorphic ventricular tachycardia is a rare occurrence with limited contemporary reports, warranting reevaluation in clinical electrophysiology.
Does intravenous atropine induce ventricular arrhythmias in patients with unexplained syncope?
Case Report (n=1)
Does intravenous atropine induce ventricular arrhythmias in patients with unexplained syncope?
Intravenous atropine can rarely induce polymorphic ventricular tachycardia, highlighting the arrhythmogenic potential of sudden autonomic shifts.
Answers are grounded in this paper and cite their sources.
Rare atropine-induced polymorphic VT warrants caution in syncope evaluation; hypothesis-generating for autonomic arrhythmia triggers.
Atropine is commonly a used pre anesthetic medication. A 22-year-old female with history of unexplained recurrent syncope during electrophysiology developed inducible ventricular arrhythmias when 0.5 mg of atropine was injected intravenously to improve this Wenckebach. There is a significant change in the autonomic influence on the heart prior to idiopathic ventricular tachycardia and this seems to result mainly from decreased vagal activity.
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Gujja et al. (2010) conducted a case report in Unexplained recurrent syncope (n=1). Atropine was evaluated on Inducible ventricular arrhythmias. Intravenous injection of of atropine induced polymorphic ventricular tachycardia in a 22-year-old female with unexplained recurrent syncope.
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