Key result
Aspirin and colchicine successfully resolve post-cardiac injury syndrome following distal coronary perforation.
Why the study?
Coronary artery perforation is a rare but serious complication of PCI that is often unrecognized during the procedure, causing delayed diagnosis and worsened prognosis.
Case Report (n=1)
No
This case report demonstrates that distal coronary artery perforation complicated by pericardial effusion can be successfully managed medically.
May support aspirin-colchicine for post-perforation pericarditis in select cases; leaves open need for prospective confirmation before broader adoption.
BACKGROUND: Coronary artery perforation is a rare but serious complication of percutaneous coronary interventions, that may eventually lead to major and fatal events such as myocardial infarction, cardiac tamponade, and ultimately death. The risk of coronary artery perforation is more significant during complex procedures as chronic total occlusions but it can occur in other circumstances such as oversized stents and/or balloons, excessive post-dilatation, and the use of hydrophilic wires. Coronary artery perforation is often not recognized during the procedure and the diagnosis is frequently not made until later when the patient develops signs related to pericardial effusion. Thus, causing a delay in management and worsening the prognosis. CASE PRESENTATION: We report a case of a distal coronary artery perforation secondary to using a hydrophilic guide in a young male patient of 52-year-old arab, initially presented with an ST-segment elevation myocardial infarction, complicated by pericardial effusion that was treated medically with a favorable outcome. CONCLUSIONS: This work highlights that coronary artery perforation is a complication that must be anticipated in high-risk situations and its diagnosis must be made early to allow adequate management.
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Faraj et al. (2023) conducted a case report in Post-cardiac injury syndrome due to coronary artery perforation (n=1). Medical management (Aspirin and Colchicine) was evaluated on Clinical improvement and regression of pericardial effusion. Medical management with aspirin and colchicine successfully treated post-cardiac injury syndrome secondary to distal coronary artery perforation caused by a hydrophilic guidewire.
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