Key result
Viral RNA and infectious Foot-and-Mouth Disease Virus could be successfully recovered from positive lateral-flow devices following electroporation into BHK-21 cells, supporting their use for dry sample transportation.
Population
Foot-and-mouth disease virus positive samples representing four FMDV serotypes
Design
Preclinical
Authors
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Supports dry FMDV sample transport via lateral-flow devices; leaves open field validation and broader pathogen applicability.
Antigen lateral-flow devices can be effectively used for the dry, non-hazardous transportation of FMDV samples for subsequent molecular characterization and virus recovery.
Fowler et al. (2014) studied Foot-and-Mouth Disease Virus (FMDV). Lateral-flow devices (LFDs) for dry transportation of FMDV vs. Robotically extracted RNA (MagNA pure) / direct passage was evaluated on Recovery of viral RNA and infectious FMDV. Viral RNA and infectious Foot-and-Mouth Disease Virus could be successfully recovered from positive lateral-flow devices following electroporation into BHK-21 cells, supporting their use for dry sample transportation.
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