Key result
Diastolic heart failure linked to ~38% lower AV junction displacement vs normal controls.
Why the study?
Left atrioventricular plane displacement reflects dysfunction in heart failure and has been reported to decrease with progression of diastolic dysfunction, but quantitative assessment using cine MRI is needed.
Can conventional cine MRI measure differences in left ventricular atrioventricular plane displacement between normal subjects and patients with diastolic dysfunction?
Cross-Sectional (n=16)
No
Can conventional cine MRI measure differences in left ventricular atrioventricular plane displacement between normal subjects and patients with diastolic dysfunction?
This study aims to quantify left ventricular atrioventricular plane displacement using cine MRI to assess diastolic dysfunction.
Cine MRI detects reduced atrioventricular displacement in diastolic HF; leaves open its diagnostic utility pending prospective validation.
Left atrioventricular plane displacement reflects the dysfunction in patients with heart failure. In previous studies, it has been reported that the displacement was decreased with progression of diastolic dysfunction [ 1 , 2 ]. The purpose of our study is to use conventional cine magnetic resonance imaging to measure the displacement of the atrioventricular plane of the left ventricle in normal subjects and in patients with diastolic dysfunction.
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Anand et al. (2010) conducted a cross-sectional in Diastolic heart failure (n=16). Diastolic heart failure vs. Normal volunteers was evaluated on 2-chamber maximum AVJ displacement (mm). Patients with diastolic heart failure had decreased atrioventricular junction displacement compared to normal volunteers (mean maximum displacement -14 mm and -11.1 mm vs -17.9 mm).
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