Why the study?
The influence of infarction localization on signal averaged electrocardiogram (SAE) parameters and their relation to severe ventricular arrhythmia prediction was unclear.
Does the localization of myocardial infarction (inferior vs anterior) affect signal averaged electrocardiogram parameters?
Cross-Sectional (n=160)
No
Does the localization of myocardial infarction (inferior vs anterior) affect signal averaged electrocardiogram parameters?
Absolute Event Rate: 41% vs 6%
p-value: p=<0.01
The localization of myocardial infarction significantly affects signal-averaged ECG parameters, with inferior MI showing higher rates of abnormal values, which should be considered when using SAE to predict severe ventricular arrhythmias.
加算平均心電図 (SAE: Signal Averaged Electrocardiogram) に対し梗塞部位がどのような影響を与えるかについて検討した.前壁梗塞66名, 下壁梗塞44名のSAEを記録し, 三つの指標―f-QRS, D40, V40を計測し, 比較した.下壁梗塞群では, 前壁梗塞群に比し, D40は有意に延長 (27.6±8.1msecvs35.2±13.2msec) , V40は有意に低値 (49.6±35.1μVvs32.7±22.3μV) であった (p<0.01) .また, 指標の異常値 (f-QRS≧120msec, D40≧39msec, V40<20μV) を有する頻度も, 3%vs20%, 9%vs36%, 6%vs41%と前壁梗塞群に比し, 下壁梗塞群で有意に高率であった (p<0.01) .さらにこれら各指標値の梗塞部位による差は, 心室頻拍を有する群でも, 有しない群でも同様の傾向が認められた.心筋梗塞部位のSAEに対する影響は大きく, 重症心室性不整脈発生の予知指標としてSAEを使用する際, 考慮が必要であると思われた.
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Mio Kawabata (1989) conducted a cross-sectional in Old myocardial infarction (n=160). Inferior myocardial infarction vs. Anterior myocardial infarction was evaluated on Frequency of abnormal V40 (<20μV) (p=<0.01).
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