Key result
The ASFV B117L gene encodes a small membrane protein that assists in the permeabilization of the ER-derived envelope during infection.
The ASFV gene B117L encodes a small membrane protein involved in permeabilizing the ER-derived envelope during infection.
B117L membrane protein data may inform ASFV countermeasures; leaves open its role in pathogenesis and as a target.
ASFV is responsible for an extensively distributed pandemic causing important economic losses in the pork industry in Eurasia. The development of countermeasures is partially limited by the insufficient knowledge regarding the function of the majority of the more than 150 genes present on the virus genome. Here, we provide data regarding the functional experimental evaluation of a previously uncharacterized ASFV gene, B117L. Our data suggest that the B117L gene encodes a small membrane protein that assists in the permeabilization of the ER-derived envelope during ASFV infection.
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Gladue et al. (2023) studied African Swine Fever Virus (ASFV) infection. ASFV gene B117L was evaluated on Functional experimental evaluation of B117L gene. The ASFV B117L gene encodes a small membrane protein that assists in the permeabilization of the ER-derived envelope during infection.
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