Key result
Human parechovirus detected in ~8% of pediatric gastroenteritis cases, revealing a novel HPeV10 genotype.
Why the study?
The prevalence and genetic diversity of human parechovirus in children with acute gastroenteritis in Sri Lanka were not well characterized.
Cross-Sectional (n=362)
No
A novel human parechovirus genotype, HPeV10, was identified in children with acute gastroenteritis in Sri Lanka, suggesting HPeV should be included in routine screening for this condition.
May warrant HPeV testing in unexplained pediatric gastroenteritis; leaves open HPeV10 pathogenicity and epidemiology.
Of 362 fecal samples collected from children with acute gastroenteritis in Sri Lanka during 2005-2006, 30 (8.3%) were positive for human parechovirus (HPeV) by reverse transcription-PCR. A novel HPeV, designated as HPeV10, was identified in 2 samples by sequence analysis of the viral protein 1 gene of the detected HPeVs.
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Pham et al. (2009) conducted a cross-sectional in Acute gastroenteritis (n=362). Human parechovirus infection was evaluated on Detection of human parechovirus (HPeV). Screening of 362 children with acute gastroenteritis in Sri Lanka revealed an 8.3% positivity rate for human parechovirus and identified a novel genotype, HPeV10.
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