Key result
Recent CIED-IE diagnosis is linked to ~87% lower 1-year mortality compared to earlier eras.
Why the study?
Studies investigating cardiac implantable electronic device infective endocarditis epidemiological changes and prognosis over long periods were lacking.
Does diagnosis in the modern era (2001-2020) improve one-year outcomes in patients with cardiac implantable electronic device infective endocarditis compared to the historical era (1981-2000)?
Comparison
CIED-IE episodes diagnosed in 1981–2000 vs 2001–2020
Design
Retrospective single-center cohort study
Follow-up
1 year
Authors
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Rising CIED-IE incidence with improved survival despite sicker patients supports vigilance; leaves open need for prospective confirmation of trends.
Cohort (n=138)
No
Does diagnosis in the modern era (2001-2020) improve one-year outcomes in patients with cardiac implantable electronic device infective endocarditis compared to the historical era (1981-2000)?
Hazard Ratio: 0.13 (95% CI 0.02–0.71)
Absolute Event Rate: 15% vs 24%
Over a 40-year period, CIED-IE episodes increased and involved older, more comorbid patients with more resistant infections, yet one-year survival improved.
Hernández‐Meneses et al. (2022) conducted a cohort in Cardiac implantable electronic device infective endocarditis (CIED-IE) (n=138). Diagnosis in the second period (2001-2020) vs. Diagnosis in the first period (1981-2000) was evaluated on One-year mortality (HR 0.13, 95% CI 0.02-0.71). Diagnosis of CIED-IE in the 2001-2020 period was associated with better one-year outcomes compared to 1981-2000 (HR 0.13; 95% CI 0.02-0.71), despite an older and more comorbid population.
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