Key result
Thin filament area is larger in I-bands than A-band S-zones regardless of sarcomere length.
Why the study?
The variation in thin filament size within different sarcomere regions of frog skeletal muscle and its relationship to thick filaments was not fully characterized.
Population
Sartorius muscle of Rana esculenta
Comparison
Thin filament area in I-bands vs S-zones of A-bands
Design
Electron microscopy with image analysis using high-resolution TV system and microdensitometer
Authors
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Thin filament area constancy in frog muscle is hypothesis-generating; leaves open extension to mammalian cardiac sarcomeres.
Orsi et al. (1988) studied this question. The area of thin filaments in the I-bands of frog skeletal muscle was significantly larger than in the S-zones of the A-bands, independent of sarcomere length.
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