Key result
Moderate-intensity eccentric cycling cuts oxygen consumption ~52% vs concentric cycling in COPD.
Why the study?
The cardiorespiratory, metabolic, and perceptual responses to eccentric versus concentric cycling in COPD patients were not well characterized.
Does eccentric cycling induce lower cardiorespiratory, metabolic, and perceptual responses compared to concentric cycling in patients with moderate COPD?
RCT (n=10)
Open-label
Randomized crossover
No
Does eccentric cycling induce lower cardiorespiratory, metabolic, and perceptual responses compared to concentric cycling in patients with moderate COPD?
Effect estimate: 52% reduction
Absolute Event Rate: 0.5% vs 1.1%
p-value: p=<0.001
Moderate-intensity eccentric cycling induces lower cardiorespiratory, metabolic, and perceptual demands than concentric cycling at the same workload in patients with moderate COPD.
Eccentric cycling may lower cardiorespiratory demand in moderate COPD; hypothesis-generating and requires randomized confirmation before practice change.
We aimed to compare the cardiorespiratory, metabolic, and perceptual responses to high- and moderate-intensity eccentric cycling versus moderate-intensity concentric cycling in chronic obstructive pulmonary disease (COPD) patients. Ten patients with moderate COPD (forced expiratory volume in 1 s (FEV1) = 68.6% ± 20.4% of predicted; 68.3 ± 9.1 years) performed 30 min of moderate-intensity concentric (CONC-M: 50% maximum workload; Wmax), moderate-intensity eccentric (ECC-M: 50% Wmax), and high-intensity eccentric (ECC-H: 100% Wmax) cycling. Average power output, oxygen consumption (V̇O2), minute ventilation (VE), respiratory frequency (fR), oxygen saturation (SpO2), heart rate (HR), systolic and diastolic blood pressure (SBP and DBP), rate of perceived exertion (RPE), and dyspnea were measured during cycling. Compared with CONC-M, lower V̇O2 (–52% ± 14%), VE (–47% ± 16%), fR (–21% ± 14%), HR (–14% ± 16%), SBP (–73% ± 54%), RPE (–36% ± 26%), and dyspnea (–41% ± 37%) were found during ECC-M. During ECC-H, a similar metabolic demand to CONC-M was found. However, average power output was 117% ± 79% higher during ECC-H. Eccentric cycling can be safely performed by COPD patients and induced lower cardiorespiratory, metabolic, and perceptual responses than concentric exercise when performed at the same workload. Novelty Moderate- and high-intensity eccentric cycling can be performed by COPD patients. Moderate-intensity eccentric cycling showed lower cardiorespiratory, metabolic, and perceptual demand than concentric cycling at the same workload in COPD patients. Even at double workload, eccentric cycling induces lower cardiorespiratory, metabolic, and perceptual demand than moderate-intensity concentric cycling.
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Nickel et al. (2020) conducted an RCT in Chronic Obstructive Pulmonary Disease (COPD) (n=10). Eccentric cycling vs. Concentric cycling at 50% Wmax was evaluated on Oxygen consumption (VO2) (52% reduction, p=<0.001). Moderate-intensity eccentric cycling reduced oxygen consumption by 52% compared to moderate-intensity concentric cycling in patients with COPD.
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