Key result
Peritoneal dialysis ultrafiltration linked to zero hypervolemia hospitalizations in refractory heart failure.
Why the study?
Hypervolemia in heart failure patients resistant or inappropriate for diuretics requires effective volume control strategies such as ultrafiltration with peritoneal dialysis.
Does peritoneal dialysis for ultrafiltration improve volume control and prevent hospitalizations in refractory heart failure patients?
Observational (n=4)
No
Does peritoneal dialysis for ultrafiltration improve volume control and prevent hospitalizations in refractory heart failure patients?
Peritoneal dialysis with a single daily icodextrin exchange may provide effective volume control and prevent hospitalizations in selected patients with refractory heart failure.
Supports PD for volume control in select refractory HF; leaves open confirmation in prospective trials.
Background: Hypervolemia is an important consequence of heart failure (HF) that leads to poor quality of life and frequent hospitalizations. Ultrafiltration (UF) with dialysis is an option for HF patients who are resistant or inappropriate for diuretics. Peritoneal dialysis (PD) can be a long-term efficient solution for hypervolemia in appropriate HF patients. Material and Methods: We retrospectively evaluated PD patients in our center in order to determine the ones whose indication was UF for volume control because of HF between January 2015 and January 2020. Results: 4 (2 females, 68.75±4.27 years old) HF patients who had a poor volume control on diuretic based regimen were on PD for UF. PD treatment was planned as a daily single exchange with icodextrin in whom all had preserved renal function. In one patient one daily exchange with an amino acid-based PD solution was added. The exchange volume was between 1000 and 1500 mL, dwell time was 9 to 14 hours, and UF was 200 to 1100 mL. During the follow-up, patients lost adequate weight and none of them were hospitalized because of hypervolemia. Conclusions: UF through PD in HF patients provides effective volume control, relief of symptoms, and avoids frequent hospitalizations. A single daily exchange with icodextrin can be adequate for hypervolemic, well-selected HF patients.
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Oruç et al. (2020) conducted an observational in Refractory congestive heart failure (n=4). Ultrafiltration through peritoneal dialysis was evaluated on Hospitalization because of hypervolemia. Ultrafiltration through peritoneal dialysis provided effective volume control and resulted in zero hospitalizations due to hypervolemia during follow-up in 4 patients with refractory congestive heart failure.
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