Key result
Short-term beta-blockade fails to impair maximal exercise performance or workload in mild hypertension.
Why the study?
The effects of cardioselective and nonselective β-blockade on dynamic exercise performance in mildly hypertensive men were not fully understood.
Do cardioselective and nonselective beta-blockers reduce maximal work load during dynamic exercise in mildly hypertensive men?
RCT
Double-blind
Do cardioselective and nonselective beta-blockers reduce maximal work load during dynamic exercise in mildly hypertensive men?
Short-term effective beta-blockade does not limit maximal physical performance during dynamic exercise in mildly hypertensive men.
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Allows β-blocker use in active mild hypertension without exercise restriction; extends RCT data on preserved maximal work load under adrenergic blockade.
Leenen et al. (1980) conducted an RCT in Mild hypertension. Atenolol and propranolol vs. Placebo was evaluated on Maximal work load during bicycle exercise until exhaustion. Cardioselective and nonselective beta-blockade for 1 week did not limit maximal physical performance or affect maximal work load during short-term dynamic exercise in mildly hypertensive men.
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