Key result
Coronary stenting shows 0 recurrent spasm-related hospitalizations in severe refractory coronary spasm.
Why the study?
Coronary stenting for severe coronary artery spasm refractory to aggressive pharmacologic management was evaluated due to limited treatment options beyond medical therapy.
Does coronary stenting prevent unstable ischemia requiring hospitalization in patients with severe, medically refractory coronary artery spasm?
Case Report (n=9)
Does coronary stenting prevent unstable ischemia requiring hospitalization in patients with severe, medically refractory coronary artery spasm?
Coronary stenting may serve as a rare adjunct for focal, medically refractory coronary artery spasm, though restenosis remains a significant risk.
Answers are grounded in this paper and cite their sources.
Stenting in refractory spasm should not yet change practice; small cohort leaves open need for randomized confirmation.
We evaluated coronary stenting in nine patients with clinically severe, angiographically documented spasm refractory to aggressive pharmacologic management. No patient subsequently developed unstable ischemia requiring hospitalization as a consequence of recurrent spasm within the stent. Mechanisms of therapeutic failure included both persistent spasm and spasm in a different artery in one patient. Restenosis occurred in three patients who subsequently underwent repeat revascularization. In the rare, carefully selected patient, stents may represent an adjunct in the management of focal coronary artery spasm, although currently medical therapy remains the standard initial approach.
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Khatri et al. (2002) conducted a case report in Coronary artery spasm (n=9). Coronary stenting was evaluated on Unstable ischemia requiring hospitalization as a consequence of recurrent spasm within the stent. Coronary stenting in 9 patients with severe, refractory coronary artery spasm resulted in 0 cases of unstable ischemia requiring hospitalization due to recurrent spasm within the stent.
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